Lactoferrin. Structure and Function

Editors: Hutchens, T. William, Lonnerdal, Bo, Rumball, Sylvia V. (Eds.) springer 24 Nov 2020
286 volte




About this book


Lactoferrin is an intriguing protein with an interesting structure and several known or suggested biological activities. We feel that attention on this protein has been too limited and diffuse, partly because it has been "hidden" among other well-known iron-binding proteins such as hemoglobin, ferritin and transferrin, but also perhaps because its biological functions are so diverse. Investigators that focus on lactoferrin represent a wide variety of medical and scientific disciplines that do not usually come together. It was our intention to improve that situation with this symposium. In this book, experts from a variety of disciplines describe the present knowledge of the structural features of lactoferrin, its carbohydrate side chains and its capacity to bind different metal ions and anions.

Several of the possible physiological functions of lactoferrin are described in detail, including the role of lactoferrin in bacterial killing, its involvement in growth and proliferation, in immune function and in iron absorption. Aspects of the molecular biology of lactoferrin and its specific interactions with different cell types are also included. Finally, as lactoferrin now has become commercially available in larger quantities, possible industrial applications are discussed. The book should give the interested reader a thorough insight into our present knowledge of lactoferrin.

https://www.springer.com/gp/book/9781461360872

Bibliography:

 - Donovan Sharon M.; The Role of Lactoferrin in Gastrointestinal and Immune Development and Function: A Preclinical Perspective. The Journal of Pediatrics VOLUME 173, SUPPLEMENT , S16-S28, JUNE 01, 2016

 - Doyle Lex W. & Jeanie L. Y. Cheong. Does bovine lactoferrin prevent late-onset neonatal sepsis? The Lancet VOLUME 393, ISSUE 10170, P382-384, FEBRUARY 02, 2019

 - ELFIN Trial Investigators Group; Enteral lactoferrin supplementation for very preterm infants: a randomised placebo-controlled trial. Lancet VOLUME 393, ISSUE 10170, P423-433, FEBRUARY 02, 2019

 - Kaur Gurpreet & Geeta Gathwala. Efficacy of Bovine Lactoferrin Supplementation in Preventing Late-onset Sepsis in low Birth Weight Neonates: A Randomized Placebo-Controlled Clinical Trial. Journal of Tropical Pediatrics, Volume 61, Issue 5, October 2015, Pages 370–376

 - Legrand Dominique. Overview of Lactoferrin as a Natural Immune Modulator. The Journal of Pediatrics VOLUME 173, SUPPLEMENT , S10-S15, JUNE 01, 2016

 - Pammi Mohan & Gautham Suresh; Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants. Cochrane Database Syst. Rev.2017 Jun 28;6(6):CD007137.

 - Trend Stephanie et al.; Levels of innate immune factors in preterm and term mothers’ breast milk during the 1st month postpartum. British Journal of Nutrition Volume 115 supplement 7.

 - Awadasseid A. et al.; Initial success in the identification and management of the coronavirus disease 2019 (COVID-19) indicates human-to-human transmission in Wuhan, China. Int J Biol Sci. 2020 Apr 6;16(11):1846-1860. doi: 10.7150/ijbs.45018. eCollection 2020.

 - Binte Aziz Asma; Debate on Bacille Calmette-Guérin vaccination against COVID-19: Is it worth performing clinical trials? Biosafety and Health, 2020

 - Blaess M. et al.; COVID-19/SARS-CoV-2 Infection: Lysosomes and Lysosomotropism Implicate New Treatment Strategies and Personal Risks. Int J Mol Sci. 2020 Jul 13;21(14):4953. doi: 10.3390/ijms21144953.

 - Campione Elena et al.; Lactoferrin as Protective Natural Barrier of Respiratory and Intestinal Mucosa against Coronavirus Infection and Inflammation; Int. J. Mol. Sci. 2020, 21(14), 4903

 - Chang Raymond, Tzi Bun Ng, Wei-ZenSun; Lactoferrin as potential preventative and adjunct treatment for COVID-19; International Journal of Antimicrobial Agents Volume 56, Issue 3, September 2020, 106118

 - Church Dawson et al., App-Based Delivery of Clinical Emotional Freedom Techniques: Cross-Sectional Study of App User Self-Ratings; JMIR Mhealth Uhealth, 2020

 - Deshmukh V, et al.; COVID-19: a conundrum to decipher. Eur Rev Med Pharmacol Sci. 2020 May;24(10):5830-5841. doi: 10.26355/eurrev_202005_21378.

 - Drago-Serrano et al.; Lactoferrin: Balancing Ups and Downs of Inflammation Due to Microbial Infections; Int J Mol Sci, 2017

 - Fernández-Lázaro Diego et al.; Physical Exercise as a Multimodal Tool for COVID-19: Could It Be Used as a Preventive Strategy? Int J Environ Res Public Health

 - Jawhara et al.; Could Intravenous Immunoglobulin Collected from Recovered Coronavirus Patients Protect against COVID-19 and Strengthen the Immune System of New Patients? Int J Mol Sci, 2020

 - Mirabelli Carmen et al.; Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19; BioRxiv. Preprint. NaN NaN [revised 2020 Sep 28].

   Original articol 

 -  Root‐Bernstein Robert Age and Location in Severity of COVID‐19 Pathology: Do Lactoferrin and Pneumococcal Vaccination Explain Low Infant Mortality and Regional Differences?

   https://www.youtube.com/watch?v=GODBYRbPL00&feature=youtu.be

   Original article 

  - Sreus A. G. et al.; COVID-19 during Pregnancy and Postpartum: Antiviral Spectrum of Maternal Lactoferrin in Fetal and Neonatal Defense; Journal of Dietary Supplements; 08 Nov 2020

    Original article 

  - Universidad Peruana Cayetano Heredia; Lactoferrin for Prevention of COVID-19 in Health Care Workers

 - Università Tor Vergata - Una risposta contro il Covid-19: la glicoproteina lattoferrina, una componente dell’immunità innata

 - Zhai Xiaofeng et al; Comparison of Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein Binding to ACE2 Receptors from Human, Pets, Farm Animals, and Putative Intermediate Hosts.; J Virol. 2020 Jul 16;94(15):e00831-20. doi: 10.1128/J. Vi.00831-20. Print 2020 Jul 16.

 - Zhang Wan-Ying et al.: Molecular mechanism prediction analysis of compound Kushen injection in the treatment of COVID-19 based on network pharmacology and molecular docking. Traditional Medicine Research 2020, 5 (5): 413-424. doi: 10.12032/TMR20200518180

 - Zhang Wan-Ying et al.; Treating COVID-19 by traditional Chinese medicine: a charming strategy?Traditional Medicine Research 2020, Vol. 5 Issue (4): 178-181 

 

 

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