An online relapse prevention tool for Bipolar Disorder offers a “cheap accessible option” for people seeking support following treatment, say researchers. Bipolar Disorder (BD) is a lifelong mental health condition characterised by depression and mania. It affects one per cent of adults worldwide and costs an estimated £5.2 billion annually in England alone. It is treated with medication, yet many people continue to experience relapses. Enhanced Relapse Prevention (ERPonline) is a psychological approach developed by the Spectrum Centre for Mental Health Research. It teaches people with Bipolar Disorder (BD) to recognise and respond to early warning signs of relapse. Lead researcher Professor Fiona Lobban from the Spectrum Centre for Mental Health Research at Lancaster University said: “The key elements are identifying your individual triggers and early warning signs for both mania and depression, and developing coping strategies to manage mood changes in everyday life.”
Interferon is a crucial component of the human immune system's response to infection by herpes simplex virus type 1 (HSV-1), but how important a role it plays in determining the severity of disease and explaining why newborns are so much more susceptible to HSV-1 infection than adults remains unclear. A comprehensive review of the contribution of type I interferon (IFN) to controlling HSV-1 infection is presented in an article published in DNA and Cell Biology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the DNA and Cell Biology website until May 19, 2017. In the article entitled "The Type I Interferon Response and Age-Dependent Susceptibility to Herpes Simplex Virus Infection," Daniel Giraldo, Douglas Wilcox, and Richard Longnecker, Northwestern University Feinberg School of Medicine, Chicago, IL, provide an in-depth look at the IFN response to HSV-1 infection. The authors examine the factors that may explain why newborns infected with HSV-1 are at greater risk for serious and potentially life-threatening diseases such as herpes simplex encephalitis, whereas in adults orolabial lesions are the more likely result of HSV-1 infection.
River floods are expected to become more frequent by mid-century, and rainstorms and coastal flooding by the end of the century. From storms to flash floods, extreme weather events are becoming more common in Europe, and can wreak havoc on infrastructure such as transport, telecoms and energy systems. Policy makers, infrastructure owners and local authorities need data and decision-making tools to deal with extreme weather and its effects. The European project called RAIN, which is drawing to a close after 3 years, has designed such tools by bringing together meteorologists, engineers and sociologists to tackle the problem. The consortium recently presented its findings at a public event in Dublin, Ireland. As in all battles, knowing your enemy is key to success. The European Severe Storms Laboratory (ESSL) in Wessling, Germany, has coordinated the analysis of extreme weather events. A team of experts from the Free University of Berlin, the Finnish Meteorological Institute and the Technical University of Delft modelled the occurrence of extreme events such as snowstorms, high winds, coastal flooding and wildfires.