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Roles of lactoferrin on skin wound healing

Roles of lactoferrin on skin wound healing

01 Dicembre 2020

Abstract Skin wound healing is a complex biological process that...

Lactoferrin: a general review

Lactoferrin: a general review

30 Novembre 2020

Abstract Lactoferrin is a 703-amino acid glycoprotein originally isolated from...

Lactoferrin (LF): a natural antimicrobial protein

Lactoferrin (LF): a natural antimicrobial protein

29 Novembre 2020

ABSTRACT Improved awareness regarding diet and health linkages has motivated...

Lactoferrin: Mechanism of action, clinical significance and therapeutic relevance

Lactoferrin: Mechanism of action, clinical significance and therapeutic relevance

27 Novembre 2020

Abstract Lactoferrin is an iron binding protein involved in a...

Iron bond bovine lactoferrin for the treatment of cancers and anemia associated with cancer cachexia

Iron bond bovine lactoferrin for the treatment of cancers and anemia associated with cancer cachexia

27 Novembre 2020

AbstractThe innate immunity protein lactoferrin (Lf) since its discovery from...

Lactoferrin, a unique molecule with diverse therapeutical and nanotechnological applications.

Lactoferrin, a unique molecule with diverse therapeutical and nanotechnological applications.

26 Novembre 2020

AbstractLactoferrin (LF) is a naturally glycoprotein with iron-binding properties and...

Lactoferrin and its Role in Wound Healing - Authors: Takayama, Yoshiharu

Lactoferrin and its Role in Wound Healing - Authors: Takayama, Yoshiharu

25 Novembre 2020

About this book Lactoferrin is an iron-binding glycoprotein belonging to...

Lunedì, 17 Agosto 2020

 

The current treatments against SARS-CoV-2 have proved so far inadequate. A potent antiviral drug is yet to be discovered. Lactoferrin, a multifunctional glycoprotein, secreted by exocrine glands and neutrophils, possesses an antiviral activity extendable to SARS-Cov-2.

We performed a randomized, prospective, interventional study assessing the role of oral and intra-nasal lactoferrin to treat mild-to-moderate and asymptomatic COVID-19 patients to prevent disease evolution. Lactoferrin induced an early viral clearance and a fast clinical symptoms recovery in addition to a statistically significant reduction of D-Dimer, Interleukin-6 and ferritin blood levels. The antiviral activity of lactoferrin related to its binding to SARS-CoV-2 and cells and protein-protein docking methods, provided the direct recognition between lactoferrin and spike S, thus hindering the spike S attachment to the human ACE2 receptor and consequently virus entering into the cells.

Lactoferrin can be used as a safe and efficacious natural agent to prevent and treat COVID-19 infection.

 

Read more : https://www.biorxiv.org/content/10.1101/2020.08.11.244996v1

 

More informations: 

 https://scienzaonline.com/scienceonline-news/item/2661-immunoprotein-impairs-sars-cov-2.html

https://scienzaonline.com/scienceonline-news/item/2676-lactoferrin-as-potential-preventative-and-treatment-for-covid-19.html

https://scienzaonline.com/scienceonline-news/item/2661-immunoprotein-impairs-sars-cov-2.html

https://scienzaonline.com/medicina/item/2657-nox2-identificato-il-bersaglio-del-covid-19.html

 

 

Pubblicato in Scienceonline

 

Scienzaonline con sottotitolo Sciencenew  - Periodico
Autorizzazioni del Tribunale di Roma – diffusioni:
telematica quotidiana 229/2006 del 08/06/2006
mensile per mezzo stampa 293/2003 del 07/07/2003
Scienceonline, Autorizzazione del Tribunale di Roma 228/2006 del 29/05/06
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