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Artificial RNA editing with ADAR for gene therapy

Artificial RNA editing with ADAR for gene therapy

10 Luglio 2020

Many of the diseases caused by point mutations have no...

Care for cats? So did people along the Silk Road more than 1,000 years ago

Care for cats? So did people along the Silk Road more than 1,000 years ago

10 Luglio 2020

"Geo Ragnarr Loobrok" - Credits: Veronica Rocco and Guido Donati...

CT of coronavirus disease (COVID-19) versus CT of influenza virus pneumonia

CT of coronavirus disease (COVID-19) versus CT of influenza virus pneumonia

10 Luglio 2020

Most COVID-19 lesions located in peripheral zone and close to...

Ocean Acidification and Human Health

Ocean Acidification and Human Health

10 Luglio 2020

While ocean acidification was initially perceived as a threat only...

Sodium found to regulate the biological clock of mice

Sodium found to regulate the biological clock of mice

10 Luglio 2020

A new study from McGill University shows that increases in...

‘Homo erectus’ era compacto, achaparrado y robusto

‘Homo erectus’ era compacto, achaparrado y robusto

08 Luglio 2020

Un estudio español publicado hoy en la revista Nature Ecology...

Soy and wheat proteins helpful for building aging muscles, but not as potent as animal protein

Soy and wheat proteins helpful for building aging muscles, but not as potent as animal protein

08 Luglio 2020

On a gram for gram basis, animal proteins are more...

Researchers test COVID treatment that decreases mortality rates by 70%

Researchers test COVID treatment that decreases mortality rates by 70%

08 Luglio 2020

A cellular therapy tested on 13 intubated patients with mechanical...

Giovedì, 26 Luglio 2018

Long-term use of either cannabis or cannabis-based drugs impairs memory say researchers. The study has implications for both recreational users and people who use the drug to combat epilepsy, multiple sclerosis and chronic pain. They found that mice exposed to the drug long-term had “significant … memory impairments” and could not even discriminate between a familiar and novel object.
There is little understanding of the potential negative side effects of long-term cannabinoid exposure, though it is already known that heavy, regular cannabis use increases the risk of developing mental health problems including psychosis and schizophrenia.

More and more people are using the drug long-term due to its legalisation in several countries, while more potent varieties are available for recreational users.

Researchers from Lancaster and Lisbon Universities studied the effects of the cannabinoid drug WIN 55,212-2 in mice and found that:

  • Long-term exposure impairs learning and memory in the animals
  • Brain imaging studies showed that the drug impairs function in key brain regions involved in learning and memory
  • Long-term exposure to the drug impairs the ability of brain regions involved in learning and memory to communicate with each other, suggesting that this underlies the negative effects of the drug on memory
Pubblicato in Scienceonline
 
 
Pubblicato dalla rivista 'Scientific Reports' il risultato della prima evidenza sperimentale dei metaboliti rilasciati durante il differenziamento in vivo delle cellule staminali pluripotenti. La ricerca, diretta dai Professori Corrado Di Natale e Federica Sangiuolo, ha coinvolto i Dipartimenti di Ingegneria Elettronica, Biomedicina e Prevenzione, e Scienze e Tecnologie Chimiche dell'Universita' degli Studi di Roma Tor Vergata.

Questo risultato sostanzia un risultato precedente ottenuto in vitro dallo stesso gruppo di ricerca. Per la prima volta e' stata registrata su modelli animali un cambiamento del profilo dei composti volatili rilasciati da cellule staminali hiPSCs ("l'odore della cellule") che segnala con estrema precisione il momento esatto in cui tali cellule iniziano il loro processo di differenziamento. Le cellule iPS sono cellule staminali, derivate da cellule somatiche in cui e' stato riportato indietro l'orologio biologico. Sono in grado di differenziare in qualsiasi tipo di cellula umana specializzata, capace di svolgere funzioni specifiche (come fegato, polmoni, cuore).
Pubblicato in Medicina

 

Scienzaonline con sottotitolo Sciencenew  - Periodico
Autorizzazioni del Tribunale di Roma – diffusioni:
telematica quotidiana 229/2006 del 08/06/2006
mensile per mezzo stampa 293/2003 del 07/07/2003
Scienceonline, Autorizzazione del Tribunale di Roma 228/2006 del 29/05/06
Pubblicato a Roma – Via A. De Viti de Marco, 50 – Direttore Responsabile Guido Donati

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