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 Le 10 Azioni del Decalbero WWF per una Festa a Basso Impatto 2025

 Le 10 Azioni del Decalbero WWF per una Festa a Basso Impatto 2025

02 Dicembre 2025

Il WWF Italia, con la sua campagna Our Future, presenta...

 Il riciclo ottimizzato dei ribosomi: eIF6 fosforilato, interruttore dell'efficienza proteica

 Il riciclo ottimizzato dei ribosomi: eIF6 fosforilato, interruttore dell'efficienza proteica

01 Dicembre 2025

Uno studio innovativo condotto dall'Università Statale di Milano e dalla...

 Avanguardia Quantistica: Ricercatori della Sapienza Realizzano il Primo Teletrasporto tra Nodi Multilab

 Avanguardia Quantistica: Ricercatori della Sapienza Realizzano il Primo Teletrasporto tra Nodi Multilab

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L'obiettivo primario di molteplici studi nel campo della meccanica quantistica...

 Il Segreto del Respiro: Il Fossile di Altamura Chiarisce l'Adattamento Facciale e Climatico dell'Uomo di Neanderthal

 Il Segreto del Respiro: Il Fossile di Altamura Chiarisce l'Adattamento Facciale e Climatico dell'Uomo di Neanderthal

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L'eccezionale stato di conservazione dello scheletro umano di Altamura, risalente...

Le Nanostrutture Plasmoniche Rivoluzionano il Fotovoltaico: Verso Celle Solari Più Accessibili ed Ecologiche

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Il trucco psicologico di 2 minuti che sconfigge la procrastinazione

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Proteggere il cervello: la strategia integrata mente-corpo contro l'invecchiamento infiammatorio

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Oltre le narrazioni apocalittiche: una nuova visione della sesta estinzione di massa

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Dicembre 2025
Lunedì, 16 Ottobre 2017 08:03

New antibiotic resistance genes found

 

 

 

Erik Kristiansson, Professor in biostatistics at Chalmers University of Technology

 

Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have found several previously unknown genes that make bacteria resistant to last-resort antibiotics. The genes were found by searching large volumes of bacterial DNA and the results are published in the scientific journal Microbiome. The increasing number of infections caused by antibiotic-resistant bacteria is a rapidly growing global problem. Disease-causing bacteria become resistant through mutations of their own DNA or by acquiring resistance genes from other, often harmless, bacteria. By analysing large volumes of DNA data, the researchers found 76 new types of resistance genes. Several of these genes can provide bacteria with the ability to degrade carbapenems, our most powerful class of antibiotics used to treat multi-resistant bacteria. “Our study shows that there are lots of unknown resistance genes. Knowledge about these genes makes it possible to more effectively find and hopefully tackle new forms of multi-resistant bacteria”, says Erik Kristiansson, Professor in biostatistics at Chalmers University of Technology and principal investigator of the study.

Pubblicato in Scienceonline

 

L’aumento delle temperature e della frequenza di eventi climatici estremi, come le ondate di caldo che si verificano in molte parti del mondo, sono destinati a portare ad un calo delle rese produttive delle più importanti colture alla base dell’alimentazione umana. Oggi, con la decifrazione della sequenza del genoma del miglio perlato, un progetto che ha coinvolto un team internazionale di 65 scienziati appartenenti a 30 diverse istituzioni di ricerca, è possibile svelare le strategie vincenti messe in atto da questa coltura per affrontare condizioni climatiche estreme. L’analisi della variabilità genetica di un migliaio di linee di questo cereale, tipicamente ben adattato a crescere nelle regioni desertiche, ha permesso di comprendere meglio come esso possa sopravvivere a temperature estreme (oltre 42°C) e sia eccezionalmente tollerante al secco. Lo studio, pubblicato sulla prestigiosa rivista Nature Biotechnology(doi:10.1038/nbt.3943), getta le basi per il potenziale sviluppo di analoghe strategie adattative in altri importanti cereali. La ricerca, co-diretta dall'International Crops Research Institute for Semi-Arid Tropics (Icrisat), India, dal Beijing Genomics Institute (Bgi)-Shenzhen, Cina e dall’Istituto nazionale di ricerca per lo sviluppo sostenibile (Ird), Francia, e che ha visto anche il coinvolgimento dell’Istituto di biologia e biotecnologia agraria del Consiglio nazionale delle ricerche (Ibba-Cnr) di Milano, “ha impiegato le tecnologie di sequenziamento e analisi del Dna più innovative per identificare nuovi strumenti genetici, come marcatori molecolari correlati alla tolleranza alla siccità e alle alte temperature, così come ad altri importanti caratteri (migliore profilo nutrizionale, resistenza a patogeni)”, spiega Francesca Sparvoli dell’Ibba-Cnr.

Pubblicato in Scienze Naturali
Lunedì, 16 Ottobre 2017 07:37

Infezioni da hpv e cervicocarcinoma

 

Aspetti epidemiologici dell’infezione da Hpv

 

Figura 1: Prevalenza delle infezioni da Hpv per classe d’età nella popolazione generale in Italia

 

 L’infezione da Hpv è estremamente frequente nella popolazione: si stima, infatti, che fino all’80% delle donne sessualmente attive si infetti nel corso della propria vita con un virus Hpv di qualunque tipo, e che oltre il 50% si infetti con un tipo ad alto rischio oncogeno. Una revisione sistematica di studi condotti in Italia [1] ha rilevato una prevalenza di Hpv oncogeni nella popolazione generale pari all’8%, senza differenze sostanziali fra Sud, Centro e Nord. È opportuno sottolineare che il calcolo di questa prevalenza ha considerato solo gli studi con campione casuale della popolazione; infatti gli studi che reclutano donne che si presentano spontaneamente a un ambulatorio ginecologico riportano una stima di prevalenza generalmente più alta degli studi che reclutano le donne in base a un invito attivo della popolazione generale. Questo probabilmente, è dovuto al fatto che le donne che accedono spontaneamente agli ambulatori ginecologici hanno, in proporzione variabile, pregressi Pap test positivi.

Pubblicato in Medicina

 

 

Human papillomavirus type 18 (HPV18) is the second most common oncogenic HPV genotype, responsible for ∼15% of cervical cancers worldwide. In this study, we constructed a full HPV18 transcription map using HPV18-infected raft tissues derived from primary human vaginal or foreskin keratinocytes. By using 5' rapid amplification of cDNA ends (RACE), we mapped two HPV18 transcription start sites (TSS) for early transcripts at nucleotide (nt) 55 and nt 102 and the HPV18 late TSS frequently at nt 811, 765, or 829 within the E7 open reading frame (ORF) of the virus genome. HPV18 polyadenylation cleavage sites for early and late transcripts were mapped to nt 4270 and mainly to nt 7299 or 7307, respectively, by using 3' RACE.

Pubblicato in Scienceonline

 

The levels of mercury in the Oslofjord cod has increased over the last 30 years, despite reduced emissions of this toxic element. In the same period, the average size of sampled cod has increased. Are the elevated levels of mercury simply a result of larger cod? Historical use and emissions of mercury have resulted in its leaking into the environment, and mercury has found its way to the Oslofjord cod. Mercury has toxic effects on the nerve system, and may have negative impacts on fine motor skills, cognitive abilities, attentiveness and memory. The Norwegian Institute of Water Research (NIVA) has been monitoring the mercury levels in the Oslofjord cod since 1984, and now a group of researchers can present the latest news about the fish in a newly published research article. This article may uncover the reasons behind the mysterious increase in mercury over the last thirty years.

More mercury

In several studies researchers have been investigating the processes by which mercury is taken up in wildlife. One would think that the mercury levels in wildlife were reduced over the last years, considering the deposition of mercury in Southeast Norway is reduced. But more intense rainfalls have increased wash-out of humus substances in inland waters, and in those environments mercury has possibly become more available for uptake in organisms, by processes that the researchers do not yet fully understand. Theoretically, this could contribute to the changes also observed in the Oslofjord cod. Another explanation for the elevated mercury levels could be a change in cod diet towards more contaminated prey. Unfortunately, there is no historic prey data available for comparison. NIVA researcher Anders Ruus still thinks they have come closer to an answer.

- Our analyses indicate that close to a third of the variation in mercury concentration was explained solely by variation in fish length, says Ruus.

Thus, it seems like bigger fish size causes higher mercury levels.

- The average length of the sampled Oslofjord cod has increased over the last decades, and this might be the main explanation of the pronounced increase in mercury levels. When we corrected the data for fish length, there was no significant increase in mercury concentrations.

Loves proteins

The concept of bigger and older organisms having higher levels of certain toxicants is well-established in the field of toxicology. It is called bioaccumulation: a toxicant is more easily absorbed through feed than excreted, and over time, the toxicant accumulates in the organism. Pure mercury is not readily taken up in organisms; but in aquatic environments where oxygen is not present, small microbes can transform mercury to methyl mercury. This substance easily binds to proteins. By this mechanism mercury enters the food chain, and the concentration builds up for each level in the chain. The compound is stored in protein-rich tissue like muscles, which is the part of the cod that humans prefer to eat. By this route, humans are also exposed.

Why is the cod larger?

There are two possible explanations to why the Oslofjord cod is bigger: Either there has been a change in the cod population, or there has been a shift in the sampling methods towards fishing larger cod.

- Beach seine surveys in the Inner Oslofjord have shown that cod recruitment has been low since the beginning of the 2000s. In 2014 there were no young fish observed at all, says Ruus.

The reason for these changes in the cod population is unknown, and this needs to be investigated further.

But the fact that there is a tolerance for fish length in the protocol for selecting fish could cause the analyses to show a trend that isn’t necessarily real.

- Since we started monitoring in the mid-eighties, there has been an increasing number of chemical parameters to be analysed, demanding sampling of more tissue per fish. As there is a tolerance for fish length in the protocol, we cannot exclude the possibility of a bias towards sampling more of the larger fish, even if all guidelines have been followed, Ruus explains.

Anyhow, length cannot be the only factor causing the increase in mercury, Ruus emphasizes. More research is needed to investigate other explaining factors.

This study was done by the Norwegian Institute of Water Research (NIVA) with economic support from the Research Council of Norway. Data collection is part of the Norwegian contribution to OSPAR´s (Oslo and Paris Commission) Joint Assessment and Monitoring Programme (JAMP). This is conducted by NIVA by contract from the Norwegian Environment Agency.

 

http://www.niva.no/en/stor-torsk-har-meir-kvikksoelv

Pubblicato in Scienceonline
Venerdì, 13 Ottobre 2017 16:44

IL MIGLIORE AMICO DEL COLEOTTERO

 

Osmo-dog il primo cane molecolare per il monitoraggio del coleottero Osmoderma eremita, specie protetta dalla Ue e marker della qualità ambientale

 

Teseo, il golden retriever addestrato sotto la guida di Paolo Audisio del Dipartimento di Biologia e biotecnologie C. Darwin della Sapienza, si è rivelato uno strumento funzionale per scovare le larve di Osmoderma eremita, una specie classificata, all’interno del progetto europeo Mipp (Monitoraggio di insetti con la partecipazione pubblica), come "prossima alla minaccia" e ormai rara in gran parte dei paesi europei. L'obiettivo principale del progetto – iniziato alla fine del 2012 e terminato il 30 settembre 2017 – è stato quello di sviluppare metodi standard e non invasivi per il monitoraggio di alcune specie di coleotteri saproxilici, fra i quali appunto Osmoderma eremita. Tra i beneficiari associati del progetto, la Sapienza ha seguito l’addestramento di Osmodog, un cane da ricerca per la conservazione, che individua le larve di Osmoderma eremita nel loro habitat, cioè all’interno di cavità di vecchi e grandi alberi (querce, castagni, salici, faggi, pioppi ecc.), una nicchia ecologica molto ristretta e in costante riduzione.

Pubblicato in Scienza generale

 

Researchers from Universidad Politécnica de Madrid (UPM) and National Institute for Agricultural Research and Experimentation (INIA) have studied the effects of using zinc oxide nanoparticles on agriculture. A research carried out at School of Agricultural, Food and Biosystems Engineering (ETSIAAB) from UPM in collaboration with researchers from Ecotoxicology group of INIA, has studied how zinc oxide nanoparticles affect tomato and bean plants. The effects found depended on the type of crop, exposure time, and especially soil pH. The results, which have been published in Science of the Total Environment journal, suggest that the use of these nanoparticles does not pose a toxicity risk for these crops and this would allow us to use their good fertilizing properties as a source of zinc micronutrient. The deliberate application of nanoparticles in agriculture, although incipient, is promising. Due to their small size, the nanoparticles have different properties from the same material in their regular size. Essentially, they have a high specific area and a high surface energy that produce changes in its physicochemical, optical and electrical properties, as well as a high reactivity.

Pubblicato in Scienceonline

 

 

The emergence of antibiotic-resistant microbial strains risks severely limiting yields in animal production chains in the coming decades, exacerbating the existing poverty in numerous countries. Experts from CIRAD and their partners analysed the policies implemented in Southeast Asia and identified a series of actions required to fight effectively against antimicrobial resistance, in line with the One Health approach. Their conclusions have been published in the prestigious journal BMJ.

Antimicrobial resistance is a threat to health and to the economy

Antibiotics are regularly used in livestock or fish production, to fight disease, boost productivity or prevent contamination of the food chain. This almost blanket use has led to the development, in both humans and animals, of resistant microbial strains against which conventional antibiotics no longer have any effect. In September 2016, the United Nations recognized that the emergence of antimicrobial resistance on a global scale was a threat to health and human development. In particular, recent projections estimated that by 2050 global livestock production would fall by 3% to 8% each year, resulting in substantial economic losses, particularly in the world's poorest countries.

Pubblicato in Scienceonline

 

 

Girls who skipped breakfast as part of a study into energy intake and physical activity were found to consume 350 fewer calories *(kcals) a day. Most adults need around 2,000 kcal a day Researchers looked at the eating and physical activity habits of 40 teenage girls over three days and how the omission of breakfast affected their daily energy intake. They found that the girls ate, on average, an extra 115 calories, when they missed breakfast compared with days when they ate a **standard breakfast provided by the researchers. However, they also calculated that the breakfast provided to the girls contained 468 calories, so the net intake for total calories consumed in one day was -353 calories when they skipped breakfast. Dr Keith Tolfrey, of Loughborough University, who co-authored the paper, Effect of breakfast omission and consumption on energy intake and physical activity in adolescent girls, said that people who eat breakfast are less likely to be overweight or obese, but our research showed that eating breakfast increased total energy intake in girls over the short term.

Pubblicato in Scienceonline

 

At the ongoing EU-hosted Our Ocean conference in Malta (5-6 October), the European Union has committed to 36 tangible actions to foster healthier, cleaner, safer and more secure seas. Amounting to over €550 million and involving activities worldwide, the announcements underline the EU's determination to improve the situation of the seas and send a positive signal of encouragement to the rest of the world – governments and private sector alike - to step up and tackle the growing ocean challenges, from plastic pollution and protecting marine life to the impact of climate change and criminal activities at sea.

The EU's 36 commitments are described in detail below.

Maritime security is the basis for global trade and prosperity, but it is under threat - from natural disasters to piracy, trafficking and armed conflict. To make our oceans safer and more secure the European Union announced:

  • €37.5 million to ensure maritime security and counter piracy along the south-eastern African coastline and in the Indian Ocean. The funds are to be implemented by four regional organisations (IGAD, COMESA, EAC and IOC) in cooperation with UNODC, INTERPOL and FAO. The programme supports alternative livelihood initiatives in the coastal pirate areas of Somalia, investigation capacities at national and regional level, prison reforms, prosecution and judicial capacity, disruption of illegal financial flows, combating money laundering, and various other maritime tasks, in addition to a regional mechanism for the coordination and exchange of maritime information.
  • €4 million of investment in its satellite monitoring programme (Copernicus) in 2017 to support EU agencies and EU Member States in monitoring oil pollution and large-scale commercial fisheries (including the fight against illegal, unreported and unregulated fishing) in the Northeast Atlantic, the Mediterranean, the Baltic, the North Sea, the Black Sea, the Pacific Ocean and around the Canary Islands. Copernicus will also introduce new services to support law enforcement and navigation safety in ice-infested areas.
  • continued support for maritime security in the Gulf of Guinea, including through the Gulf of Guinea Inter-Regional Network and the launch of two new programmes: the SWAIMS programme (Support to West Africa Integrated Maritime Security), worth €29 million, and the programme to improving port security in West and Central Africa, worth €8.5 million.
  • €1 million in 2017 to support the upgrading of the ICT systems of EU maritime authorities and facilitate cooperation between them. Furthermore, the European Union announced that it will contribute €80,000 to facilitate cooperation between coastguard authorities in Europe.
  • the launch of a prototype surveillance tool in September 2017 which detects ships to reveal the extent of human activities at sea. The 'Search for Unidentified Maritime Objects' tool, or 'SUMO' for short, is a piece of software that automatically analyses data from radar imaging satellites to find vessels as small as 1 metre long, even in cloudy conditions or at night. The SUMO tool is open source, to promote uptake by users and developers and facilitate international cooperation on mapping of ship routes, monitoring shipping intensity, identifying polluting ships, monitoring fishing activities, countering piracy and smuggling, and controlling maritime borders.
Pubblicato in Scienceonline

Medicina

 Il riciclo ottimizzato dei ribosomi: eIF6 fosforilato, interruttore dell'efficienza proteica

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 Le 10 Azioni del Decalbero WWF per una Festa a Basso Impatto 2025

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Scienzaonline con sottotitolo Sciencenew  - Periodico
Autorizzazioni del Tribunale di Roma – diffusioni:
telematica quotidiana 229/2006 del 08/06/2006
mensile per mezzo stampa 293/2003 del 07/07/2003
Scienceonline, Autorizzazione del Tribunale di Roma 228/2006 del 29/05/06
Pubblicato a Roma – Via A. De Viti de Marco, 50 – Direttore Responsabile Guido Donati

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